Plasma digoxin concentration in children with heart failure.
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چکیده
منابع مشابه
Plasma digoxin concentration in children with heart failure.
A dosage schedule for digoxin medication is presented which has proved effective and safe in children of different ages with heart failure due to a variety of cardiac conditions. The plasma digoxin concentrations during maintenance therapy, using this schedule, agree closely with previously reported therapeutic adult plasma concentrations, though the results do not exclude the efficiency and sa...
متن کاملAssociation of serum digoxin concentration and outcomes in patients with heart failure.
CONTEXT The Digitalis Investigation Group (DIG) trial reported that digoxin provided no overall mortality benefit and only a modest reduction in hospitalizations among patients with heart failure and depressed left ventricular systolic function. The clinical outcomes associated with digoxin therapy at different serum concentrations in the DIG trial have not been assessed. OBJECTIVE To assess ...
متن کاملMeasurement of plasma digoxin concentration by radioimmunoassay.
A rapid, sensitive, and precise method for measuring the plasma digoxin concentration has been developed with the radioimmunoassay technique. Seventy patients receiving digoxin were shown to have plasma digoxin concentrations between 0.4 and 5 ng./ml. Preliminary studies show that though there is a positive correlation between total daily dose and the plasma digoxin concentration, the relations...
متن کاملDigoxin in heart failure and cardiac arrhythmias.
HEART FAILURE Digoxin therapy has no effect on mortality in heart failure. Digoxin may be useful for maintaining clinical stability and exercise capacity in patients with symptomatic heart failure. Digoxin appears to be of most benefit in patients with severe heart failure, cardiomegaly and a third heart sound. Digoxin should be used as a second-line drug after diuretics, angiotensin-converting...
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Macklem, P T (1975). The use of a helium-oxygen mixture during maximum expiratory flow to demonstrate obstruction in small airways in smokers. Journal of Clinical Investigation, 55, 1090-1099. Fry, D L, and Hyatt, R E (1960). Pulmonary mechanics. American Journal of Medicine, 29, 672-689. Hogg, J C, Macklem, P T, and Thurlbeck, W M (1968). Site and nature of airway obstruction in chronic obstru...
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ژورنال
عنوان ژورنال: BMJ
سال: 1973
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5865.550